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Resveratrol antagonizes thyroid hormone-induced expression of checkpoint and proliferative genes in oral cancer cells

Background/purpose: Dysregulation of cell cycle checkpoint control may lead to the independence of growth regulating signals. Checkpoint protein such as the PD-1/PD-L1 immune checkpoint involving tumor cells and host immune defense lymphocytes is a well-studied therapeutic target in oncology. Acting...

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Bibliographic Details
Main Authors: Chia-Cheng Lin, Yu-Tang Chin, Ya-Jung Shih, Yi-Ru Chen, Yao-Yu Chung, Chi-Yu Lin, Chao-Nan Hsiung, Jacqueline Whang-Peng, Sheng-Yang Lee, Hung-Yun Lin, Paul J. Davis, Kuan Wang
Format: Artigo
Language:Inglês
Published: Elsevier 2019-09-01
Series:Journal of Dental Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790219300650
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