Individualized Mutation Detection in Circulating Tumor DNA for Monitoring Colorectal Tumor Burden Using a Cancer-Associated Gene Sequencing Panel.

BACKGROUND:Circulating tumor DNA (ctDNA) carries information on tumor burden. However, the mutation spectrum is different among tumors. This study was designed to examine the utility of ctDNA for monitoring tumor burden based on an individual mutation profile. METHODOLOGY:DNA was extracted from a to...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Kei A Sato, Tsuyoshi Hachiya, Takeshi Iwaya, Kohei Kume, Teppei Matsuo, Keisuke Kawasaki, Yukito Abiko, Risaburo Akasaka, Takayuki Matsumoto, Koki Otsuka, Satoshi S Nishizuka
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science (PLoS) 2016-01-01
Σειρά:PLoS ONE
Διαθέσιμο Online:http://europepmc.org/articles/PMC4699643?pdf=render
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