Individualized Mutation Detection in Circulating Tumor DNA for Monitoring Colorectal Tumor Burden Using a Cancer-Associated Gene Sequencing Panel.

BACKGROUND:Circulating tumor DNA (ctDNA) carries information on tumor burden. However, the mutation spectrum is different among tumors. This study was designed to examine the utility of ctDNA for monitoring tumor burden based on an individual mutation profile. METHODOLOGY:DNA was extracted from a to...

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Hlavní autoři: Kei A Sato, Tsuyoshi Hachiya, Takeshi Iwaya, Kohei Kume, Teppei Matsuo, Keisuke Kawasaki, Yukito Abiko, Risaburo Akasaka, Takayuki Matsumoto, Koki Otsuka, Satoshi S Nishizuka
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2016-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC4699643?pdf=render
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