Epigenetic Silencing of miR-9 Promotes Migration and Invasion by EZH2 in Glioblastoma Cells

Glioblastoma (GBM) is the most common primary brain tumor in adults. Tumor invasion is the major reason for treatment failure and poor prognosis in GBM. Inhibiting migration and invasion has become an important therapeutic strategy for GBM treatment. Enhancer of zeste homolog 2 (EZH2) and C-X-C moti...

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Bibliographic Details
Main Authors: Yi-Chung Chien, Jia-Ni Chen, Ya-Huey Chen, Ruey-Hwang Chou, Han-Chung Lee, Yung-Luen Yu
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
enhancer of zeste homolog 2
CXCR4
miR-9
glioblastoma
invasion
Online Access:https://www.mdpi.com/2072-6694/12/7/1781
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