TGF-β-Induced CD8+CD103+ Regulatory T Cells Show Potent Therapeutic Effect on Chronic Graft-versus-Host Disease Lupus by Suppressing B Cells

Lupus nephritis is one of most severe complications of systemic erythematosus lupus and current approaches are not curative for lupus nephritis. Although CD4+Foxp3+ regulatory T cells (Treg) are crucial for prevention of autoimmunity, the therapeutic effect of these cells on lupus nephritis is not s...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Haowen Zhong, Ya Liu, Zhenjian Xu, Peifeng Liang, Hui Yang, Xiao Zhang, Jun Zhao, Junzhen Chen, Sha Fu, Ying Tang, Jun Lv, Julie Wang, Nancy Olsen, Anping Xu, Song Guo Zheng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2018-01-01
श्रृंखला:Frontiers in Immunology
विषय:
TGF-β1
CD8+CD103+ iTreg
lupus nephritis
immunosuppression
B cell responses
ऑनलाइन पहुंच:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00035/full
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