Dectin-3 Recognizes Glucuronoxylomannan of Cryptococcus neoformans Serotype AD and Cryptococcus gattii Serotype B to Initiate Host Defense Against Cryptococcosis

Cryptococcus neoformans and Cryptococcus gattii cause life-threatening meningoencephalitis or lung diseases in immunocompetent individuals or immunocompromised ones. C. neoformans and C. gattii are subdivided into five serotypes based on their capsular glucuronoxylomannan (GXM). C. neoformans consis...

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Bibliographic Details
Main Authors: Hua-Rong Huang, Fan Li, Hua Han, Xia Xu, Ning Li, Shunchun Wang, Jin-Fu Xu, Xin-Ming Jia
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
innate immunity
C-type lectin receptor
Dectin-3
Crytococcus
glucuronoxylomannan
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01781/full
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