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A Single Injection of Human Neutralizing Antibody Protects against Zika Virus Infection and Microcephaly in Developing Mouse Embryos

Summary: Zika virus (ZIKV) is a mosquito-transmitted flavivirus that is generally benign in humans. However, an emergent strain of ZIKV has become widespread, causing severe pre- and post-natal neurological defects. There is now an urgent need for prophylactic and therapeutic agents. To address this...

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Autors principals: Cui Li, Fei Gao, Lei Yu, Ruoke Wang, Yisheng Jiang, Xuanling Shi, Chibiao Yin, Xiaoping Tang, Fuchun Zhang, Zhiheng Xu, Linqi Zhang
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018-05-01
Col·lecció:Cell Reports
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2211124718305345
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