Development of assays using hexokinase and phosphoglucomutase gene sequences that distinguish strains of Leishmania tropica from different zymodemes and microsatellite clusters and their application to Palestinian foci of cutaneous leishmaniasis.

BACKGROUND/OBJECTIVES: Palestinian strains of L.tropica characterized by multilocus enzyme electrophoresis (MLEE) fall into two zymodemes, either MON-137 or MON-307. METHODOLOGY/PRINCIPLE FINDINGS: Assays employing PCR and subsequent RFLP were applied to sequences found in the Hexokinase (HK) gene,...

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Main Authors: Kifaya Azmi, Gabriele Schonian, Lionel F Schnur, Abedelmajeed Nasereddin, Suheir Ereqat, Ziad Abdeen
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2013-01-01
叢編:PLoS Neglected Tropical Diseases
在線閱讀:http://europepmc.org/articles/PMC3784506?pdf=render
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