Development of assays using hexokinase and phosphoglucomutase gene sequences that distinguish strains of Leishmania tropica from different zymodemes and microsatellite clusters and their application to Palestinian foci of cutaneous leishmaniasis.

BACKGROUND/OBJECTIVES: Palestinian strains of L.tropica characterized by multilocus enzyme electrophoresis (MLEE) fall into two zymodemes, either MON-137 or MON-307. METHODOLOGY/PRINCIPLE FINDINGS: Assays employing PCR and subsequent RFLP were applied to sequences found in the Hexokinase (HK) gene,...

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Библиографические подробности
Главные авторы: Kifaya Azmi, Gabriele Schonian, Lionel F Schnur, Abedelmajeed Nasereddin, Suheir Ereqat, Ziad Abdeen
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2013-01-01
Серии:PLoS Neglected Tropical Diseases
Online-ссылка:http://europepmc.org/articles/PMC3784506?pdf=render
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