PRMT1 Is Critical for the Transcriptional Activity and the Stability of the Progesterone Receptor

Summary: The progesterone receptor (PR) is an inducible transcription factor that plays critical roles in female reproductive processes and in several aspects of breast cancer tumorigenesis. Our report describes the type I protein arginine methyltransferase 1 (PRMT1) as a cofactor controlling proges...

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Main Authors: Lucie Malbeteau, Coralie Poulard, Cécile Languilaire, Ivan Mikaelian, Frédéric Flamant, Muriel Le Romancer, Laura Corbo
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020-06-01
Serija:iScience
Teme:
Molecular Biology
Molecular Mechanism of Gene Regulation
Molecular Interaction
Cancer
Online dostop:http://www.sciencedirect.com/science/article/pii/S2589004220304211
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