Genetic Diagnosis of Familial Hypercholesterolemia in Asia

Familial hypercholesterolemia (FH) is a common genetic disease with an incidence of about 1 in 200–500 individuals. Genetic mutations markedly elevate low-density lipoprotein cholesterol and atherosclerotic cardiovascular disease (ASCVD) in FH patients. With advances in clinical diagnosis and geneti...

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Main Authors: Chin-Chou Huang, Min-Ji Charng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-07-01
Serier:Frontiers in Genetics
Fag:
apolipoprotein B
Asia
diagnosis
familial hypercholesterolemia
gene
low-density lipoprotein receptor
Online adgang:https://www.frontiersin.org/article/10.3389/fgene.2020.00833/full
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