The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy

In the last years, immunotherapy with antibodies against programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1) has shown remarkable efficacy in the treatment of different types of tumours, representing a true revolution in oncology. While its efficacy has initially been attrib...

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Main Authors: Linda Quatrini, Francesca Romana Mariotti, Enrico Munari, Nicola Tumino, Paola Vacca, Lorenzo Moretta
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2020-11-01
Series:Cancers
Assuntos:
PD-1
PD-L1
NK cells
inhibitory checkpoints
tumour microenvironment
immunotherapy
Acceso en liña:https://www.mdpi.com/2072-6694/12/11/3285
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