Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly

Recent approval of chimeric antigen receptor (CAR) T cell therapy by the European Medicines Agency (EMA)/Federal and Drug Administration (FDA) and the remarkable results of CAR T clinical trials illustrate the curative potential of this therapy. While CARs against a multitude of different antigens a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Stijn De Munter, Alexander Van Parys, Layla Bral, Joline Ingels, Glenn Goetgeluk, Sarah Bonte, Melissa Pille, Lore Billiet, Karin Weening, Annick Verhee, Jose Van der Heyden, Tom Taghon, Georges Leclercq, Tessa Kerre, Jan Tavernier, Bart Vandekerckhove
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2020-01-01
श्रृंखला:International Journal of Molecular Sciences
विषय:
nanobody
vhh
chimeric antigen receptor
car t cell
cd33
cd20
pcr
gibson assembly
nanocar
ऑनलाइन पहुंच:https://www.mdpi.com/1422-0067/21/3/883
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