Fish Oil Supplementation Reduces Inflammation but Does Not Restore Renal Function and Klotho Expression in an Adenine-Induced CKD Model

Background: Chronic kidney disease and inflammation promote loss of Klotho expression. Given the well-established anti-inflammatory effects of omega-3 fatty acids, we aimed to investigate the effect of fish oil supplementation in a model of CKD. Methods: Male C57BL/6 mice received supplementation wi...

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Main Authors: Juan S. Henao Agudelo, Leandro C. Baia, Milene S. Ormanji, Amandda R. P. Santos, Juliana R. Machado, Niels O. Saraiva Câmara, Gerjan J. Navis, Martin H. de Borst, Ita P. Heilberg
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2018-09-01
Series:Nutrients
Assuntos:
klotho
CKD
fish oil
fibrosis
inflammation
Acceso en liña:http://www.mdpi.com/2072-6643/10/9/1283
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