Fish Oil Supplementation Reduces Inflammation but Does Not Restore Renal Function and Klotho Expression in an Adenine-Induced CKD Model

Background: Chronic kidney disease and inflammation promote loss of Klotho expression. Given the well-established anti-inflammatory effects of omega-3 fatty acids, we aimed to investigate the effect of fish oil supplementation in a model of CKD. Methods: Male C57BL/6 mice received supplementation wi...

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Hlavní autoři: Juan S. Henao Agudelo, Leandro C. Baia, Milene S. Ormanji, Amandda R. P. Santos, Juliana R. Machado, Niels O. Saraiva Câmara, Gerjan J. Navis, Martin H. de Borst, Ita P. Heilberg
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2018-09-01
Edice:Nutrients
Témata:
klotho
CKD
fish oil
fibrosis
inflammation
On-line přístup:http://www.mdpi.com/2072-6643/10/9/1283
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