Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity

Abstract Background The pathology of chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and most lung cancers involves the small airway epithelium (SAE), the single continuous layer of cells lining the airways ≥ 6th generations. The basal cells (BC) are the stem/progen...

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書誌詳細
主要な著者: Guoqing Wang, Howard H. Lou, Jacqueline Salit, Philip L. Leopold, Sharon Driscoll, Juergen Schymeinsky, Karsten Quast, Sudha Visvanathan, Jay S. Fine, Matthew J. Thomas, Ronald G. Crystal
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2019-08-01
シリーズ:Respiratory Research
主題:
Small airway
Basal cells
Immortalization
Telomerase
Single cell
オンライン･アクセス:http://link.springer.com/article/10.1186/s12931-019-1140-9
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