The Warburg Effect Is Associated With Tumor Aggressiveness in Testicular Germ Cell Tumors

Testicular Germ Cell Tumors (TGCTs) are a rare group of neoplasms and the most common solid malignancy arising in young male adults. Despite the good response of these tumors to platinum-based chemotherapy, some patients are refractory to treatment and present poor clinical outcomes. During carcinog...

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Main Authors: Murilo Bonatelli, Eduardo C. A. Silva, Flavio M. Cárcano, Maurício G. Zaia, Luiz F. Lopes, Cristovam Scapulatempo-Neto, Céline Pinheiro
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-06-01
Serier:Frontiers in Endocrinology
Fag:
immunohistochemistry
metabolic reprogramming
testicular germ cell tumors
testicular neoplasms
Warburg effect
Online adgang:https://www.frontiersin.org/article/10.3389/fendo.2019.00417/full
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