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Fetuin-A deficiency protects mice from Experimental Autoimmune Encephalomyelitis (EAE) and correlates with altered innate immune response.
Fetuin-A is a biomarker of disease activity in multiple sclerosis. Our aim was to investigate whether Fetuin-A plays a direct role in the neuroinflammatory response in the mouse EAE model. Peak Fetuin-A expression in the CNS and in peripheral lymphoid tissue correlated with peak EAE disease activity...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Public Library of Science (PLoS)
2017-01-01
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Schriftenreihe: | PLoS ONE |
Online Zugang: | http://europepmc.org/articles/PMC5384772?pdf=render |
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