ALS1 Deletion Increases the Proportion of Small Cells in a Candida albicans Culture Population: Hypothesizing a Novel Role for Als1

Candida albicans Als1 is a large cell-surface glycoprotein most often discussed for its role in mediating ligand-binding and aggregative interactions. Relative to a wild-type control, deletion of ALS1 produced a strain that showed delayed germ-tube formation and delayed disease progression in a muri...

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Bibliographic Details
Main Authors: Xiaomin Zhao, Soon-Hwan Oh, David A. Coleman, Lois L. Hoyer
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Candida albicans
cell size
agglutinin-like sequence family
germ tube
murine model
disseminated candidiasis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.895068/full
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