Display of Porcine Epidemic Diarrhea Virus Spike Protein on Baculovirus to Improve Immunogenicity and Protective Efficacy

A new variant of the porcine epidemic diarrhea virus (PEDV) is an emerging swine disease, killing considerable numbers of neonatal piglets in North America and Asia in recent years. To generate immunogens mimicking the complex spike (S) protein folding with proper posttranslational modification to m...

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Autores principales: Chia-Yu Chang, Wei-Ting Hsu, Yu-Chan Chao, Hui-Wen Chang
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2018-06-01
Colección:Viruses
Materias:
baculovirus display system
PEDV
spike vaccine
intramuscular injection
Acceso en línea:http://www.mdpi.com/1999-4915/10/7/346
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