Display of Porcine Epidemic Diarrhea Virus Spike Protein on Baculovirus to Improve Immunogenicity and Protective Efficacy

A new variant of the porcine epidemic diarrhea virus (PEDV) is an emerging swine disease, killing considerable numbers of neonatal piglets in North America and Asia in recent years. To generate immunogens mimicking the complex spike (S) protein folding with proper posttranslational modification to m...

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Bibliographic Details
Main Authors: Chia-Yu Chang, Wei-Ting Hsu, Yu-Chan Chao, Hui-Wen Chang
Format: Artigo
Language:Inglês
Published: MDPI AG 2018-06-01
Series:Viruses
Subjects:
baculovirus display system
PEDV
spike vaccine
intramuscular injection
Online Access:http://www.mdpi.com/1999-4915/10/7/346
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