Changes in Ca2+ Removal Can Mask the Effects of Geometry During IP3R Mediated Ca2+ Signals

Calcium (Ca2+) signals are ubiquitous. Most intracellular Ca2+ signals involve the release of Ca2+ from the endoplasmic reticulum (ER) through Inositol 1,4,5-Trisphosphate Receptors (IP3Rs). The non-uniform spatial organization of IP3Rs and the fact that their individual openings are coupled via cyt...

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Main Authors: Estefanía Piegari, Cecilia Villarruel, Silvina Ponce Dawson
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019-07-01
Serija:Frontiers in Physiology
Teme:
calcium signaling
spatiotemporal distribution
buffers
oocyte maturation
IP3R distribution
Online dostop:https://www.frontiersin.org/article/10.3389/fphys.2019.00964/full
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