Survival-related genes are diversified across cancers but generally enriched in cancer hallmark pathways

Abstract Background Pan-cancer studies have disclosed many commonalities and differences in mutations, copy number variations, and gene expression alterations among cancers. Some of these features are significantly associated with clinical outcomes, and many prognosis-predictive biomarkers or biosig...

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Main Authors: Po-Wen Wang, Yi-Hsun Su, Po-Hao Chou, Ming-Yueh Huang, Ting-Wen Chen
Format: Artigo
Jezik:Inglês
Izdano: BMC 2022-05-01
Serija:BMC Genomics
Teme:
Survival
Pan-cancer
Biomarker
Univariate analysis
Cox proportional hazards model
Log-rank test
Online dostop:https://doi.org/10.1186/s12864-022-08581-x
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