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Dynamic expression of Notch signaling genes in neural stem/progenitor cells
In neural stem/progenitor cells, expression of the Notch effector Hes1, a transcriptional repressor, oscillates with a period of 2-3 hours by negative feedback, and Hes1 oscillations induce the oscillatory expression of the proneural gene Neurogenin2 (Ngn2) and the Notch ligand gene Delta-like1 (Dll...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2011-06-01
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| シリーズ: | Frontiers in Neuroscience |
| 主題: | |
| オンライン･アクセス: | http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00078/full |
| タグ: |
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