Integrin α3/α6 and αV are implicated in ADAM15-activated FAK and EGFR signalling pathway individually and promote non-small-cell lung cancer progression

Abstract Disintegrin-metalloproteinase 15(ADAM15), a member of disintegrin metalloproteinases (ADAMs), plays important roles in various cancer types. However, the underlying ADAM15 functioning in lung cancer is still unclear. In the present study, we find that ADAM15 regulates the epidermal growth f...

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Main Authors: Jieqi Zhou, Anqi Wang, Tingting Cai, Yue Li, Wenwen Du, Yang Zhang, Ruochen Zhang, Weijie Zhang, Jianjie Zhu, Yuanyuan Zeng, Jian-an Huang, Zeyi Liu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2022-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04928-0
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