Delayed administration of suramin attenuates peritoneal fibrosis in rats

Abstract Background Peritoneal fibrosis is the most common complication of peritoneal dialysis, but there is currently no effective treatment. We previously reported that suramin pretreatment prevents the development of peritoneal fibrosis in a rat model of peritoneal fibrosis induced by chlorhexidi...

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Main Authors: Chongxiang Xiong, Na Liu, Xiaofei Shao, Sairah Sharif, Hequn Zou, Shougang Zhuang
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2019-11-01
Series:BMC Nephrology
Assuntos:
Suramin
Peritoneal fibrosis
Epidermal growth factor receptor
Signal transducers, activator of transcription 3
Extracellular signal-regulated kinases ½
Acceso en liña:http://link.springer.com/article/10.1186/s12882-019-1597-2
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