Graphene oxide-PLGA hybrid nanofibres for the local delivery of IGF-1 and BDNF in spinal cord repair

Spinal cord injury (SCI) can lead to permanent and severe functional impairment below the lesion level and is still one of the most challenging clinical problems. The treatment of SCI has progressed with the development of tissue engineering techniques. Insulin-like growth factor 1 (IGF-1) and brain...

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Hlavní autoři: Su Pan, Zhiping Qi, Qiuju Li, Yue Ma, Chuan Fu, Shuang Zheng, Weijian Kong, Qinyi Liu, Xiaoyu Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2019-12-01
Edice:Artificial Cells, Nanomedicine, and Biotechnology
Témata:
Spinal cord injury
neural stem cells
insulin-like growth factor 1
brain derived neurotrophic factor
graphene oxide
neurogenesis
On-line přístup:https://www.tandfonline.com/doi/10.1080/21691401.2019.1575843
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