Co-expression network analysis identifies a gene signature as a predictive biomarker for energy metabolism in osteosarcoma

Abstract Background Osteosarcoma (OS) is a common malignant bone tumor originating in the interstitial tissues and occurring mostly in adolescents and young adults. Energy metabolism is a prerequisite for cancer cell growth, proliferation, invasion, and metastasis. However, the gene signatures assoc...

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Main Authors: Naiqiang Zhu, Jingyi Hou, Guiyun Ma, Shuai Guo, Chengliang Zhao, Bin Chen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-06-01
Serier:Cancer Cell International
Fag:
Gene signature
Energy metabolism
Least absolute shrinkage and selection operator
Osteosarcoma
Prognosis biomarker
Weighted co-expressed network analysis
Online adgang:http://link.springer.com/article/10.1186/s12935-020-01352-2
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