Revealing the Complexity of Breast Cancer by Next Generation Sequencing

Over the last few years the increasing usage of “-omic” platforms, supported by next-generation sequencing, in the analysis of breast cancer samples has tremendously advanced our understanding of the disease. New driver and passenger mutations, rare chromosomal rearrangements and other genomic aberr...

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Bibliographische Detailangaben
Hauptverfasser: John Verigos, Angeliki Magklara
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2015-11-01
Schriftenreihe:Cancers
Schlagworte:
breast cancer
next-generation sequencing
intratumor heterogeneity
driver genes
targeted therapy
gene fusions
Online Zugang:http://www.mdpi.com/2072-6694/7/4/0885
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