Time-Course Transcriptome Analysis for Drug Repositioning in Fusobacterium nucleatum-Infected Human Gingival Fibroblasts

Fusobacterium nucleatum (F. nucleatum) is a crucial periodontal pathogen and human gingival fibroblasts (GFs) are the first line of defense against oral pathogens. However, the research on potential molecular mechanisms of host defense and effective treatment of F. nucleatum infection in GFs remains...

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Autori principali: Wenyan Kang, Zhilong Jia, Di Tang, Xiaojing Zhao, Jinlong Shi, Qian Jia, Kunlun He, Qiang Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019-09-01
Serie:Frontiers in Cell and Developmental Biology
Soggetti:
F. nucleatum
gingival fibroblasts
RNA-seq
time-course transcriptome
drug repositioning
Accesso online:https://www.frontiersin.org/article/10.3389/fcell.2019.00204/full
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