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Design, Synthesis, and Biological Evaluation of a New Series of Biphenyl/Bibenzyl Derivatives Functioning as Dual Inhibitors of Acetylcholinesterase and Butyrylcholinesterase

Alzheimer’s disease (AD), the most common form of dementia in adults, is a progressive neurodegenerative disorder of the brain characterized by loss of memory and steady deterioration of cognition. Here, a series of symmetrical molecules containing biphenyl/bibenzyl scaffolds (12–36) were designed,...

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Main Authors: Dong-mei Wang, Bo Feng, Hui Fu, Ai-lin Liu, Lin Wang, Guan-hua Du, Song Wu
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2017-01-01
Serija:Molecules
Teme:
Online dostop:http://www.mdpi.com/1420-3049/22/1/172
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