Recent Advances in ω-Transaminase-Mediated Biocatalysis for the Enantioselective Synthesis of Chiral Amines

Chiral amines are important components of 40–45% of small molecule pharmaceuticals and many other industrially important fine chemicals and agrochemicals. Recent advances in synthetic applications of ω-transaminases for the production of chiral amines are reviewed herein. Althoug...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mahesh D. Patil, Gideon Grogan, Andreas Bommarius, Hyungdon Yun
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2018-06-01
Schriftenreihe:Catalysts
Schlagworte:
biocatalysis
chiral amines
ω-transaminases
protein engineering
reaction engineering
multi-enzymatic cascades
Online Zugang:http://www.mdpi.com/2073-4344/8/7/254
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