miR-221-3p Delivered by BMMSC-Derived Microvesicles Promotes the Development of Acute Myelocytic Leukemia

Objective: The study aims to investigate the effects of miR-221-3p in bone marrow mesenchymal stem cell (BMMSC)-derived microvesicles (MVs) on cell cycle, proliferation and invasion of acute myelocytic leukemia (AML).Methods: Bioinformatics was used to predict differentially expressed miRNAs (DEmiRN...

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Main Authors: Xuewu Zhang, Yu Xu, Jinghan Wang, Shuqi Zhao, Jianhu Li, Xin Huang, Huan Xu, Xiang Zhang, Shanshan Suo, Yunfei Lv, Yi Zhang, Wenjuan Yu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-02-01
Serier:Frontiers in Bioengineering and Biotechnology
Fag:
BMMSC
microvesicles
miR-221-3p
AML
cell proliferation and invasion
cell cycle
Online adgang:https://www.frontiersin.org/article/10.3389/fbioe.2020.00081/full
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