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The Expression of the fim Operon Is Crucial for the Survival of Streptococcus parasanguinis FW213 within Macrophages but Not Acid Tolerance.

The acquisition of transition metal ions is essential for the viability and in some cases the expression of virulence genes in bacteria. The fimCBA operon of Streptococcus parasanguinis FW213 encodes a Mn(2+)/Fe(2+)-specific ATP-binding cassette transporter. FimA, a lipoprotein in the system, is ess...

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Autori principali: Yi-Ywan M Chen, Hui-Ru Shieh, Ya-Ching Chang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3688865?pdf=render
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