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Mutations in Caenorhabditis elegans actin, which are equivalent to human cardiomyopathy mutations, cause abnormal actin aggregation in nematode striated muscle [version 1; peer review: 1 approved, 3 approved with reservations]
Actin is a central component of muscle contractile apparatuses, and a number of actin mutations cause diseases in skeletal, cardiac, and smooth muscles. However, many pathogenic actin mutations have not been characterized at cell biological and physiological levels. In this study, we tested whether...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
F1000 Research Ltd
2019-03-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-279/v1 |
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