Angelica polysaccharide moderates hypoxia-evoked apoptosis and autophagy in rat neural stem cells by downregulation of BNIP3

Neonatal hypoxia–ischemia is a troublesome disease. Angelica polysaccharide (AP) is proved to have antioxidant effects. Our study was performed to confirm the effects of AP in hypoxia-exposed neural stem cells (NSCs). NSCs were pre-treated with AP and then stimulated with hypoxia. Viability of NSCs...

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Main Authors: Yongzhen Xue, Dongmei Li, Yige Zhang, Hang Gao, Hui Li
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis Group 2019-12-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Assuntos:
Neonatal hypoxia–ischemia
angelica polysaccharide
BNIP3
mTOR
Notch
Acceso en liña:https://www.tandfonline.com/doi/10.1080/21691401.2019.1623228
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