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Teasing apart translational and transcriptional components of stochastic variations in eukaryotic gene expression.

The intrinsic stochasticity of gene expression leads to cell-to-cell variations, noise, in protein abundance. Several processes, including transcription, translation, and degradation of mRNA and proteins, can contribute to these variations. Recent single cell analyses of gene expression in yeast hav...

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Main Authors: Raheleh Salari, Damian Wojtowicz, Jie Zheng, David Levens, Yitzhak Pilpel, Teresa M Przytycka
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2012-01-01
叢編:PLoS Computational Biology
在線閱讀:http://europepmc.org/articles/PMC3431295?pdf=render
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