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Bedside testing of CYP2C19 gene for treatment of patients with PCI with antiplatelet therapy

Abstract Background To mitigate the risk of stent thrombosis, patients treated by percutaneous coronary intervention (PCI) are administered dual anti-platelet therapy comprising aspirin and a platelet P2Y12 receptor inhibitor. Clopidogrel is a prodrug requiring activation by the cytochrome P450 enzy...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Abdullah M. Al-Rubaish, Fahad A. Al-Muhanna, Abdullah M. Alshehri, Mohammed A. Al-Mansori, Rudaynah A. Alali, Rania M. Khalil, Khalid A. Al Faraidy, Cyril Cyrus, Mohammed M. Sulieman, Chittibabu Vatte, Daniel M. F. Claassens, Jurriën M. ten Berg, Folkert W. Asselbergs, Amein K. Al-Ali
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2020-06-01
Cyfres:BMC Cardiovascular Disorders
Pynciau:
Mynediad Ar-lein:http://link.springer.com/article/10.1186/s12872-020-01558-2
Tagiau: Ychwanegu Tag
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