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Impaired Sarcoplasmic Reticulum Calcium Uptake and Release Promote Electromechanically and Spatially Discordant Alternans: A Computational Study

Cardiac electrical dynamics are governed by cellular-level properties, such as action potential duration (APD) restitution and intracellular calcium (Ca) handling, and tissue-level properties, including conduction velocity restitution and cell–cell coupling. Irregular dynamics at the cellular level...

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Главный автор: Seth H. Weinberg
Формат: Artigo
Язык:Inglês
Опубликовано: SAGE Publishing 2016-01-01
Серии:Clinical Medicine Insights: Cardiology
Online-ссылка:https://doi.org/10.4137/CMC.S39709
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