Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis

Three HIV-1-seronegative patients with disseminated tuberculosis presented significant depletion of T-cell counts, in CD4+ and/or CD8+ cells, associated with increased expression of activation marker CD38 on CD8+ T-lymphocytes. This finding raises the question of potential mechanisms involved in the...

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Bibliografiska uppgifter
Huvudupphovsmän: Denise Silva Rodrigues, Reinaldo Salomão, Esper Georges Kallas
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier
Serie:Brazilian Journal of Infectious Diseases
Ämnen:
Mycobacterium tuberculosis
disseminated tuberculosis
lymphocyte
cellular activation
Länkar:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000100012&lng=en&tlng=en
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