A Promising Listeria-Vectored Vaccine Induces Th1-Type Immune Responses and Confers Protection Against Tuberculosis

Deaths associated with tuberculosis (TB) is rising and accounted for 1.4 million deaths in 2015 many of which were due to drug-resistant bacteria. Vaccines represent an important medical intervention, but the current Bacilli Calmette-Guerin (BCG) vaccine is not ideal for the protection of teenagers...

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Bibliographische Detailangaben
Hauptverfasser: Yuelan Yin, Kai Lian, Dan Zhao, Chengwu Tao, Xiang Chen, Weijun Tan, Xiaobo Wang, Zhengzhong Xu, Maozhi Hu, Yan Rao, Xiaohui Zhou, Zhiming Pan, Xiaoming Zhang, Xin'an Jiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017-09-01
Schriftenreihe:Frontiers in Cellular and Infection Microbiology
Schlagworte:
Mycobacterium tuberculosis
Th1/Th17
protective efficacy
Listeria monocytogenes
attenuated
FbpB-ESAT-6
Online Zugang:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00407/full
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