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Tumor suppressor WWOX and p53 alterations and drug resistance in glioblastomas
Tumor suppressor p53 are frequently mutated in glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene exp...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2013-03-01
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| シリーズ: | Frontiers in Oncology |
| 主題: | |
| オンライン･アクセス: | http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00043/full |
| タグ: |
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