Functions and properties of nuclear lncRNAs—from systematically mapping the interactomes of lncRNAs

Abstract Protein and DNA have been considered as the major components of chromatin. But beyond that, an increasing number of studies show that RNA occupies a large amount of chromatin and acts as a regulator of nuclear architecture. A significant fraction of long non-coding RNAs (lncRNAs) prefers to...

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Bibliografiska uppgifter
Huvudupphovsmän: Chia-Yu Guh, Yu-Hung Hsieh, Hsueh-Ping Chu
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMC 2020-03-01
Serie:Journal of Biomedical Science
Ämnen:
Long non-coding RNA
RNA-interactome
Epigenetics
Chromatin
Nuclear architecture
R-loops
Länkar:http://link.springer.com/article/10.1186/s12929-020-00640-3
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