Functions and properties of nuclear lncRNAs—from systematically mapping the interactomes of lncRNAs

Abstract Protein and DNA have been considered as the major components of chromatin. But beyond that, an increasing number of studies show that RNA occupies a large amount of chromatin and acts as a regulator of nuclear architecture. A significant fraction of long non-coding RNAs (lncRNAs) prefers to...

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Hauptverfasser: Chia-Yu Guh, Yu-Hung Hsieh, Hsueh-Ping Chu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-03-01
Schriftenreihe:Journal of Biomedical Science
Schlagworte:
Long non-coding RNA
RNA-interactome
Epigenetics
Chromatin
Nuclear architecture
R-loops
Online Zugang:http://link.springer.com/article/10.1186/s12929-020-00640-3
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