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Determination of S- and R-Amlodipine in Rat Plasma using LC-MS/MS After Oral Administration of S-Amlodipine and Racemic Amlodipine

The pharmacokinetic properties of S-amlodipine were studied using racemic amlodipine and single S-enantiomer(SK310) administration to rats. Plasma levels of the drug were determined using chiral liquid chromatography coupled with tandemmass spectrometry following solid phase extraction. The stereosp...

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Detaylı Bibliyografya
Asıl Yazarlar: Dong-Hyun Kim, Tae Kon Kim, Bong-Yong Lee, Hye Hyun Yoo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Korean Society for Mass Spectrometry 2011-12-01
Seri Bilgileri:Mass Spectrometry Letters
Online Erişim:http://Amlodipine, LC-MS/MS, Pharmacokinetics, Rat plasma
Etiketler: Etiketle
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