Expression of miR-34a in T-Cells Infected by Human T-Lymphotropic Virus 1

Human T-lymphotropic virus 1 (HTLV-1) immortalizes T-cells and is the causative agent of adult T-cell leukemia/lymphoma (ATLL). HTLV-1 replication and transformation are governed by multiple interactions between viral regulatory proteins and host cell factors that remain to be fully elucidated. The...

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Main Authors: Varun K. Sharma, Vittoria Raimondi, Katia Ruggero, Cynthia A. Pise-Masison, Ilaria Cavallari, Micol Silic-Benussi, Vincenzo Ciminale, Donna M. D’Agostino
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Microbiology
Assuntos:
HTLV-1
miR-34a
p53
nutlin-3a
adult T-cell leukemia/lymphoma
Acceso en liña:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00832/full
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