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Membrane damage elicits an immunomodulatory program in Staphylococcus aureus.
The Staphylococcus aureus HrtAB system is a hemin-regulated ABC transporter composed of an ATPase (HrtA) and a permease (HrtB) that protect S. aureus against hemin toxicity. S. aureus strains lacking hrtA exhibit liver-specific hyper-virulence and upon hemin exposure over-express and secrete immunom...
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| Main Authors: | , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science (PLoS)
2010-03-01
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| 叢編: | PLoS Pathogens |
| 在線閱讀: | http://europepmc.org/articles/PMC2837406?pdf=render |
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