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Membrane damage elicits an immunomodulatory program in Staphylococcus aureus.
The Staphylococcus aureus HrtAB system is a hemin-regulated ABC transporter composed of an ATPase (HrtA) and a permease (HrtB) that protect S. aureus against hemin toxicity. S. aureus strains lacking hrtA exhibit liver-specific hyper-virulence and upon hemin exposure over-express and secrete immunom...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science (PLoS)
2010-03-01
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| Collection: | PLoS Pathogens |
| Accès en ligne: | http://europepmc.org/articles/PMC2837406?pdf=render |
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