Progress of Induced Pluripotent Stem Cell Technologies to Understand Genetic Epilepsy

The study of the pathomechanisms by which gene mutations lead to neurological diseases has benefit from several cellular and animal models. Recently, induced Pluripotent Stem Cell (iPSC) technologies have made possible the access to human neurons to study nervous system disease-related mechanisms, a...

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Bibliographische Detailangaben
Hauptverfasser: Bruno Sterlini, Floriana Fruscione, Simona Baldassari, Fabio Benfenati, Federico Zara, Anna Corradi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-01-01
Schriftenreihe:International Journal of Molecular Sciences
Schlagworte:
epilepsy
induced pluripotent stem cells
disease modeling
cerebral organoid
neuronal excitability
transplantation
Online Zugang:https://www.mdpi.com/1422-0067/21/2/482
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