Increased circulating adiponectin in response to thiazolidinediones: investigating the role of bone marrow adipose tissue

BACKGROUND: Bone marrow adipose tissue (MAT) contributes to increased circulating adiponectin, an insulin-sensitising hormone, during caloric restriction, but whether this occurs in other contexts remains unknown. The anti-diabetic thiazolidinediones (TZDs) also promote MAT expansion and hyperadipon...

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Hlavní autoři: Richard J Sulston, Brian Scott Learman, Bofeng Zhang, Erica L Scheller, Sebastian D Parlee, Becky R Simon, Hiroyuki Mori, Adam J Bree, Robert J Wallace, Venkatesh Krishnan, Ormond A MacDougald, William P Cawthorn
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016-09-01
Edice:Frontiers in Endocrinology
Témata:
Adiponectin
brown adipose tissue
rosiglitazone
UCP1
white adipose tissue
thiazolidinedione
On-line přístup:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00128/full
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